My email is not working on my iphone.

It keeps saying my password is incorrect and my email is not updating.  I have entered the correct password multiple times in the box that pops up and in settings.  I have had this issue in the past, but mostly when travelling.  But I am at home.  It is very difficult because you often need to check your email with two factor identification.  Any ideas on how to fix this issue.  Any ideas?