No. I used the Bose remote to control the Comcast box. Now that there are voice commands, I prefer to use the Comcast remote for cable. I just have to use the other to control volume, muting, and on and off.
try reversing process and turn bose box off and do the up button until the unit comes on. watch that remote's LED to be sure it stays in search mode or ends search mode (extra flashing).